Cryptic crossword clue
Illnesses sending mum to the loo 8

The most common and most likely answer to this crossword clue is the 8 letter word MALADIES

M
A
L
A
D
I
E
S

Buddy explains!

The straight part
We know that "Illnesses" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case illnesses = maladies.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MALADIES mean?

MALADIES noun
  1. Any ailment or disease of the body; especially, a lingering or deep-seated disorder.
  2. A moral or mental defect or disorder.

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