Cryptic crossword clue
Imbue a clue into puzzle 9

The most common and most likely answer to this crossword clue is the 9 letter word INOCULATE

I've seen this crossword clue in Financial Times
I
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Buddy explains!

The straight part
We know that "Imbue" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case imbue = inoculate.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INOCULATE mean?

INOCULATE verb
  1. To introduce an antigenic substance or vaccine into something (e.g. the body) or someone, such as to produce immunity to a specific disease.
  2. (by extension) To safeguard or protect something as if by inoculation.
  3. To add one substance to another; to spike.
  4. To graft by inserting buds.
  5. To introduce into the mind (used especially of harmful ideas or principles); to imbue; to implant.

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