The most common and most likely answer to this crossword clue is the 10 letter word DISTRESSED
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More clues leading to the result DISTRESSED
- Puddings I'd sent back, upset
- Anxious — unlocked is it?
- Upset to find first of drawers has locks?
- Anxious getting bald?
- Upset from upside-down puddings I had
- Suffering as Samson was, fatally
- Diana given emphasis when much troubled
- Filled with tension faded away in poverty
- As Samson was when shorn of his locks?
- In anguish, having a shaved head?
Buddy explains!

The straight part
We know that "In anguish" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case in anguish = distressed.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DISTRESSED mean?
DISTRESSED verb- To cause strain or anxiety to someone.
- To retain someone’s property against the payment of a debt; to distrain.
- To treat a new object to give it an appearance of age.
- Anxious or uneasy
- (of merchandise, etc.) damaged
- (of a property) offered for sale after foreclosure
- (of furniture, etc.) faded or abused in order to appear old, or antique