Cryptic crossword clue
In chat room, I'd set out contents of some cells 12

The most common and most likely answer to this crossword clue is the 12 letter word MITOCHONDRIA

I've seen this crossword clue in The Times
M
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T
O
C
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A

Buddy explains!

The straight part
We know that "contents of some cells" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case contents of some cells = mitochondria.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MITOCHONDRIA mean?

MITOCHONDRIA noun
  1. A spherical or ovoid organelle found in the cytoplasm of eukaryotic cells and containing genetic material separate from that of the host; it is responsible for the conversion of food to usable energy in the form of ATP.
MITOCHONDRIA noun
  1. (sometimes proscribed) mitochondrion

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