Cryptic crossword clue
In earnest way, holding ‘er hand, off and on 14

The most common and most likely answer to this crossword clue is the 14 letter word INTERMITTENTLY

I've seen this crossword clue in The Sunday Telegraph
I
N
T
E
R
M
I
T
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L
Y

Buddy explains!

The straight part
We know that "off and on" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case off and on = intermittently.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INTERMITTENTLY mean?

INTERMITTENTLY adverb
  1. Stopping or starting at intervals.

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