The most common and most likely answer to this crossword clue is the 6 letter word CARPAL
I've seen this crossword clue in The Guardian
C
A
R
P
A
L
More clues leading to the result CARPAL
Buddy explains!

The straight part
We know that "bone" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case bone = carpal.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CARPAL mean?
CARPAL noun- Any of the eight bones of the wrist (carpus).
- Of or pertaining to the carpus.