Cryptic crossword clue
In Lib-Dem leader I will replace ace making comeback that can’t be beaten 10

The most common and most likely answer to this crossword clue is the 10 letter word INVINCIBLE

I've seen this crossword clue in The Daily Telegraph
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Buddy explains!

The straight part
We know that "that can’t be beaten" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case that can’t be beaten = invincible.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INVINCIBLE mean?

INVINCIBLE noun
  1. Someone or something that cannot be defeated, destroyed or killed.
INVINCIBLE adjective
  1. Impossible to defeat, destroy or kill; too powerful to be defeated or overcome.

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