Cryptic crossword clue
In new composition I use flat calami 8

The most common and most likely answer to this crossword clue is the 8 letter word FISTULAE

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The straight part
We know that "calami" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case calami = fistulae.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does FISTULAE mean?

FISTULAE noun
  1. An abnormal connection or passageway between organs or vessels that normally do not connect.
  2. A tube, a pipe, or a hole.
  3. The tube through which the wine of the Eucharist was once sucked from the chalice.

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