Cryptic crossword clue
In Paris, he has quit butchering for a change 8

The most common and most likely answer to this crossword clue is the 8 letter word MUTATION

I've seen this crossword clue in The Times
M
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The straight part
We know that "a change" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a change = mutation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MUTATION mean?

MUTATION noun
  1. Any alteration or change.
  2. Any heritable change of the base-pair sequence of genetic material.
  3. A mutant.
  4. An alteration a particular sound of a word, especially the initial consonant, which is triggered by the word's morphological or syntactic context and not by its phonological context.
  5. A group of thrushes.

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