Cryptic crossword clue
In retrospect rue being taken in by flyer for poisonous apple? 6

The most common and most likely answer to this crossword clue is the 6 letter word DATURA

D
A
T
U
R
A

Buddy explains!

The straight part
We know that "poisonous apple" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case poisonous apple = datura.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DATURA mean?

DATURA noun
  1. A plant of the genus Datura, known for its trumpet-shaped flowers and poisonous properties.

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