Cryptic crossword clue
In small room, old musical instrument 5

The most common and most likely answer to this crossword clue is the 5 letter word CELLO

C
E
L
L
O


Buddy explains!

The straight part
We know that "musical instrument" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case musical instrument = cello.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CELLO mean?

CELLO noun
  1. A large stringed instrument of the violin family with four strings, tuned from lowest to highest C-G-D-A, and played with a bow, also possessing an endpin to support the instrument's weight.
CELLO noun
  1. Cellophane

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