Cryptic crossword clue
In St Lucia you are travelling with care 10

The most common and most likely answer to this crossword clue is the 10 letter word CAUTIOUSLY

I've seen this crossword clue in The Guardian
C
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Buddy explains!

The straight part
We know that "with care" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case with care = cautiously.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CAUTIOUSLY mean?

CAUTIOUSLY adverb
  1. In a cautious manner.

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