Cryptic crossword clue
In the beginning, men entertaining ladies on deep-sea yachts produce sequence of pleasant notes 6

The most common and most likely answer to this crossword clue is the 6 letter word MELODY

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Buddy explains!

The straight part
We know that "sequence of pleasant notes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sequence of pleasant notes = melody.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MELODY mean?

MELODY noun
  1. Tune; sequence of notes that makes up a musical phrase

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