The most common and most likely answer to this crossword clue is the 2 plus 6 letter word AB INITIO
A
B
I
N
I
T
I
O
More clues leading to the result AB INITIO
- Selected by The X Factor, a person’s story’s entertaining from the beginning
- Throw it away into main road! That adds nothing from the start
- Right from the beginning, put that thing in a container before 10
- . Antibiotic, not fully digested, after time's lost at the start
- In the beginning, sailor in Italy has one egg
- From the beginning, Arab businessman is not inclined to import oil, for starters
Buddy explains!
The straight part
We know that "In the beginning" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case in the beginning = ab initio.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.