Cryptic crossword clue
In the time between life and death, self-pain is absurd 8

The most common and most likely answer to this crossword clue is the 8 letter word LIFESPAN

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Buddy explains!

The straight part
We know that "In the time between life and death" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case in the time between life and death = lifespan.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LIFESPAN mean?

LIFESPAN noun
  1. The length of time for which an organism lives.
  2. (by extension) The length of time for which something exists or is current or valid.

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