Cryptic crossword clue
Inability to coordinate drivers locking vehicle 6

The most common and most likely answer to this crossword clue is the 6 letter word ATAXIA

I've seen this crossword clue in Independent
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The straight part
We know that "Inability to coordinate" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case inability to coordinate = ataxia.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ATAXIA mean?

ATAXIA noun
  1. Lack of coordination while performing voluntary movements, which may appear to be clumsiness, inaccuracy, or instability.
  2. The condition of a polymer in which the orientation of the subunits is random
  3. Disorder; irregularity.

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