Cryptic crossword clue
Incensed at people rejecting seconds, start to convulse and twitch 10

The most common and most likely answer to this crossword clue is the 10 letter word APOPLECTIC

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Incensed" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case incensed = apoplectic.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does APOPLECTIC mean?

APOPLECTIC noun
  1. A person suffering from apoplexy.
APOPLECTIC adjective
  1. Of, or relating to apoplexy.
  2. Marked by extreme anger or fury.
  3. Effused with blood.

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