Cryptic crossword clue
Infestation by preying organism of some of spar as it is made 10

The most common and most likely answer to this crossword clue is the 10 letter word PARASITISM

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Buddy explains!

The straight part
We know that "Infestation by preying organism" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case infestation by preying organism = parasitism.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PARASITISM mean?

PARASITISM noun
  1. Interaction between two organisms, in which one organism (the parasite) benefits and the other (the host) is harmed.
  2. A similar interaction between people.

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