Cryptic crossword clue
Inflammation irritates badly 9

The most common and most likely answer to this crossword clue is the 9 letter word ARTERITIS

A
R
T
E
R
I
T
I
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does ARTERITIS mean?

ARTERITIS noun
  1. The inflammation of arterial walls, often due to infection or an autoimmune response.

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