Cryptic crossword clue
Initially, Calzaghe beat that boxer, one who talks a lot 10

The most common and most likely answer to this crossword clue is the 10 letter word CHATTERBOX

I've seen this crossword clue in The Guardian
C
H
A
T
T
E
R
B
O
X


Buddy explains!

The straight part
We know that "one who talks a lot" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case one who talks a lot = chatterbox.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CHATTERBOX mean?

CHATTERBOX noun
  1. An artificial intelligence program intended to simulate interactive conversation with another person
CHATTERBOX noun
  1. One who chats or talks to excess.
  2. A cootie catcher (children's fortune-telling device).

Latest crossword clues with full explanations