Cryptic crossword clue
Instrument holds second half of vial containing internal secretions 8

The most common and most likely answer to this crossword clue is the 8 letter word HORMONAL

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Buddy explains!

The straight part
We know that "containing internal secretions" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case containing internal secretions = hormonal.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HORMONAL mean?

HORMONAL adjective
  1. Pertaining to hormones.
  2. Of or pertaining to the menstrual cycle.
  3. Strongly affected by one's hormones.

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