Cryptic crossword clue
Instrument Yes then played with, always eschewing echo? 5

The most common and most likely answer to this crossword clue is the 5 letter word SYNTH

I've seen this crossword clue in Independent
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SYNTH mean?

SYNTH noun
  1. A musical synthesizer.
SYNTH verb
  1. To play on a musical synthesizer.

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