Cryptic crossword clue
Interbreeding, say, between pair of US states and European country 13

The most common and most likely answer to this crossword clue is the 13 letter word MISCEGENATION

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "Interbreeding" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case interbreeding = miscegenation.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MISCEGENATION mean?

MISCEGENATION noun
  1. (see usage notes) The mixing or blending of race in marriage or breeding, interracial marriage.
  2. A mixing or blending, especially one which is considered to be inappropriate.

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