Cryptic crossword clue
Invalid sadly losing pounds — protein required 6

The most common and most likely answer to this crossword clue is the 6 letter word AVIDIN

A
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The straight part
We know that "protein required" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case protein required = avidin.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does AVIDIN mean?

AVIDIN noun
  1. A tetrameric protein produced in the oviducts of birds, reptiles and amphibians and deposited in the whites of their eggs.

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