Cryptic crossword clue
‘Invalids’ with a nature that’s perverse? 15

The most common and most likely answer to this crossword clue is the 15 letter word VALETUDINARIANS

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VALETUDINARIANS mean?

VALETUDINARIANS noun
  1. A person in poor health or sickly, especially one who is constantly obsessed with their state of health

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