The most common and most likely answer to this crossword clue is the 10 letter word GRUMPINESS
G
R
U
M
P
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N
E
S
S
More clues leading to the result GRUMPINESS
- Sour disposition of US men, prigs being awkward
- Irascibility shown by US solider eating steak on headland
- Irritability shown by politician that’s given entry to deviant US singer
- Discontentment shown by upset partners, one afternoon, cutting short break
- 9 Irascibility shown by US solider eating steak on headland
Buddy explains!

The straight part
We know that "Irritability" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case irritability = grumpiness.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.