Cryptic crossword clue
Is yours truly coming in skinny? Organic substance needed 7

The most common and most likely answer to this crossword clue is the 7 letter word THIAMIN

I've seen this crossword clue in The Daily Telegraph
T
H
I
A
M
I
N

Buddy explains!

The straight part
We know that "Organic substance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case organic substance = thiamin.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does THIAMIN mean?

THIAMIN noun
  1. One of the constituents of vitamin B complex, found in meat, yeast and bran, that is necessary for the metabolism of carbohydrates.

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