The most common and most likely answer to this crossword clue is the 6 letter word ISCHIA
I've seen this crossword clue in The Guardian
I
S
C
H
I
A
More clues leading to the result ISCHIA
- Island savings scheme penetrated by foreign character
- Island is area for Greek character to occupy
- One’s mate missing out on North Island
- Is friend boycotting Northern island?
- Insular offshore location‘s funds protecting Greek character
- Italian island’s hip parts
- One small Church starts in India’s Andaman Island
Buddy explains!

The straight part
We know that "Island" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case island = ischia.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ISCHIA mean?
ISCHIA noun- The lowest of the three bones that make up each side of the pelvis.