The most common and most likely answer to this crossword clue is the 12 letter word DEPRIVATIONS
I've seen this crossword clue in The Daily Telegraph
D
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P
R
I
V
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Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DEPRIVATIONS mean?
DEPRIVATIONS noun- The act of depriving, dispossessing, or bereaving; the act of deposing or divesting of some dignity.
- The state of being deprived
- The taking away from a clergyman of his benefice, or other spiritual promotion or dignity.
- (followed by “of”) lack