Cryptic crossword clue
Isolated drunk staggered around Spain 10

The most common and most likely answer to this crossword clue is the 10 letter word SEGREGATED

I've seen this crossword clue in Financial Times
S
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Buddy explains!

The straight part
We know that "Isolated" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case isolated = segregated.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does SEGREGATED mean?

SEGREGATED verb
  1. To separate, especially by social policies that directly or indirectly keep races or ethnic groups apart.
SEGREGATED adjective
  1. (of a person or thing) Separated or isolated from others, or from another group.
  2. (of an institution) Having access restricted to certain groups, or excluding certain groups.

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