Cryptic crossword clue
It can be bitter, being in pursuit of liberal state 10

The most common and most likely answer to this crossword clue is the 10 letter word AFTERTASTE

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Buddy explains!

The straight part
We know that "it can be bitter" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it can be bitter = aftertaste.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does AFTERTASTE mean?

AFTERTASTE noun
  1. A taste of something that persists when it is no longer present.
  2. The persistence of the taste of something no longer present.
  3. Of wine, finish.

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