Cryptic crossword clue
It may help you go and have fun, nursing a back strain 8

The most common and most likely answer to this crossword clue is the 8 letter word LAXATIVE

I've seen this crossword clue in The Guardian
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The straight part
We know that "It may help you go" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it may help you go = laxative.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LAXATIVE mean?

LAXATIVE noun
  1. Any substance, such as a food or in the form of a medicine which has a laxative effect.
LAXATIVE adjective
  1. Having the effect of moving the bowels, or aiding digestion and preventing constipation.

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