Cryptic crossword clue
It will purge 1 down of muscly stereotypes 7

The most common and most likely answer to this crossword clue is the 7 letter word CLYSTER

I've seen this crossword clue in The Guardian
C
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Y
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Buddy explains!

The straight part
We know that "It will purge 1 down" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case it will purge 1 down = clyster.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CLYSTER mean?

CLYSTER noun
  1. A medicine applied via the rectum; an enema or suppository.

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