Cryptic crossword clue
It’s strange to be in Rome taking part in comic opera with Iris and Diana? 9

The most common and most likely answer to this crossword clue is the 9 letter word GODDESSES

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does GODDESSES mean?

GODDESSES noun
  1. A female deity.
  2. A woman honored or adored as physically attractive or of superior charm and intelligence.
  3. A woman of substantial authority or influence.

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