Cryptic crossword clue
It’s used as antifreeze in bitingly cold weather 6

The most common and most likely answer to this crossword clue is the 6 letter word GLYCOL

I've seen this crossword clue in The Daily Telegraph
G
L
Y
C
O
L

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The cryptic/wordplay part
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This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does GLYCOL mean?

GLYCOL noun
  1. Any aliphatic diol.
  2. A thick, colourless liquid, C2H4(OH)2, of a sweetish taste, produced artificially from certain ethylene compounds and used as an antifreeze; ethylene glycol.

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