Cryptic crossword clue
Jabber on pathetically, your hopes at first rising 4

The most common and most likely answer to this crossword clue is the 4 letter word HYPO

H
Y
P
O

Buddy explains!

The straight part
We know that "Jabber" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case jabber = hypo.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HYPO mean?

HYPO noun
  1. Melancholy; a fit of ‘hypochondria’; a morbid depression.
  2. A hypochondriac.
  3. Sodium thiosulphate, a photographic fixing agent.
  4. A hypoglycaemia attack in a person with diabetes.
  5. The substance sodium hyposulfite.
  6. A hypodermic syringe.
  7. Hypothecation.
  8. (in the study of law) A hypothetical case.
  9. A hypomelanistic snake.

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