The most common and most likely answer to this crossword clue is the 6 letter word JINNEE
I've seen this crossword clue in Financial Times
J
I
N
N
E
E
Buddy explains!

The straight part
We know that "spirit" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case spirit = jinnee.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does JINNEE mean?
JINNEE noun- (Muslim demonology) A genie and descendant of the jann, normally invisible to the human eye, but who may also appear in animal or human form, equivalent to demons in Jewish demonology.