The most common and most likely answer to this crossword clue is the 6 letter word JESSIE
J
E
S
S
I
E
More clues leading to the result JESSIE
Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does JESSIE mean?
JESSIE noun- (sometimes uncapitalized) A cowardly person, especially a man; an effeminate man.