Cryptic crossword clue
Japanese hottie lived with a Guys and Dolls fan

The most common and most likely answer to this crossword clue is the 6 letter word WASABI

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "Japanese hottie" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case japanese hottie = wasabi.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does WASABI mean?

WASABI noun
  1. A pungent green Japanese condiment made from the plant Eutrema japonicum (formerly Wasabia japonica).
  2. An imitation of this condiment made from horseradish with green dye.

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