Cryptic crossword clue
Jekyll’s alter ego gripped by terrible cramp sees a hippo or elephant 9

The most common and most likely answer to this crossword clue is the 9 letter word PACHYDERM

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The cryptic/wordplay part
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What does PACHYDERM mean?

PACHYDERM noun
  1. A member of the obsolete taxonomic order Pachydermata, grouping of thick-skinned, hoofed animals such as the rhinoceros, hippopotamus, elephant, pig and horse.
  2. An elephant
  3. A person with thick skin; someone who is not affected by or does not care what others say about him or her.
  4. Someone who is insensitive.

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