Cryptic crossword clue
Joint work by fifty in company science room, with speech following 13

The most common and most likely answer to this crossword clue is the 13 letter word COLLABORATION

C
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Buddy explains!

The straight part
We know that "Joint work" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case joint work = collaboration.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does COLLABORATION mean?

COLLABORATION noun
  1. The act of collaborating.
  2. A production or creation made by collaborating.
  3. Treasonous cooperation.

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