Cryptic crossword clue
Jokingly seeing son is about to shoot up 6

The most common and most likely answer to this crossword clue is the 6 letter word INJECT

I
N
J
E
C
T

Buddy explains!

The straight part
We know that "to shoot up" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case to shoot up = inject.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INJECT mean?

INJECT verb
  1. To push or pump (something, especially fluids) into a cavity or passage.
  2. To introduce (something) suddenly or violently.
  3. To administer an injection to (someone or something), especially of medicine or drugs.
  4. To take or be administered something by means of injection, especially medicine or drugs.
  5. To introduce (code) into an existing program or its memory space, often without tight integration and sometimes through a security vulnerability.
  6. To cast or throw; used with on.

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