The most common and most likely answer to this crossword clue is the 5 plus 6 letter word GREEN ONIONS
G
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N
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Buddy explains!

The straight part
We know that "Jones’s last major hit on which nobody performed work? The reverse" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case jones’s last major hit on which nobody performed work? the reverse = green onions.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.