Cryptic crossword clue
Keen to collect two blood groups — not happy 6

The most common and most likely answer to this crossword clue is the 6 letter word CRABBY

C
R
A
B
B
Y


Buddy explains!

The straight part
We know that "not happy" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case not happy = crabby.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CRABBY mean?

CRABBY adjective
  1. Visibly irritated or annoyed; grouchy, irritable, in a foul mood; given to complaining or finding fault in an annoyed way.
  2. Crabbed; difficult, or perplexing.

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