The most common and most likely answer to this crossword clue is the 8 letter word DISTRESS
D
I
S
T
R
E
S
S
More clues leading to the result DISTRESS
- Anguish produced by a girl's lock of hair
- Emphasis placed on police officer’s affliction
- Sit awkwardly in ceremonial uniform in agony
- Key is with lock in Harrow
- Misfortune to remove lock?
- Insult bunch in shock to create this?
- … 6, first in costume
- Upset one saint in costume
- Stride about ship in trouble
- Torture giving detectives bit of a shock
Buddy explains!

The straight part
We know that "Harrow" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case harrow = distress.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DISTRESS mean?
DISTRESS noun- (Cause of) discomfort.
- Serious danger.
- An aversive state of stress to which a person cannot fully adapt.
- A seizing of property without legal process to force payment of a debt.
- The thing taken by distraining; that which is seized to procure satisfaction.
- To cause strain or anxiety to someone.
- To retain someone’s property against the payment of a debt; to distrain.
- To treat a new object to give it an appearance of age.