Cryptic crossword clue
Kick off a 1978 Peace Nobelist 5

The most common and most likely answer to this crossword clue is the 5 letter word BEGIN

B
E
G
I
N

Buddy explains!

The straight part
We know that "Kick off/a 1978 Peace Nobelist" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case kick off/a 1978 peace nobelist = begin.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BEGIN mean?

BEGIN noun
  1. Beginning; start.
BEGIN verb
  1. To start, to initiate or take the first step into something.
  2. To be in the first stage of some situation
  3. To come into existence.

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