Cryptic crossword clue
Kill courier, showing mental problems … 4-3

The most common and most likely answer to this crossword clue is the 8 letter word HANG-UPS

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "mental problems" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case mental problems = hang-ups.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does HANG-UPS mean?

HANG-UPS noun
  1. An emotional difficulty or a psychological inhibition; a complex.
  2. An unforeseen obstacle to progress; a hitch.

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