Cryptic crossword clue
King’s evil woman in Misery

The most common and most likely answer to this crossword clue is the 7 letter word KILLJOY

I've seen this crossword clue in The Guardian
K
I
L
L
J
O
Y

Buddy explains!

The straight part
We know that "Misery" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case misery = killjoy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

Crossword Answer definitions

KILLJOY noun
  1. A person who is anti-fun, or prevents others from having fun.

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