Cryptic crossword clue
Knight blocking way in front of Her Majesty is just a big pussycat 7

The most common and most likely answer to this crossword clue is the 7 letter word PANTHER

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "a big pussycat" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case a big pussycat = panther.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PANTHER mean?

PANTHER noun
  1. Any of various big cats with black fur; most especially, the black-coated leopard of India.
  2. Any big cat of the genus Panthera.
  3. A cougar; especially the Florida panther.
  4. A creature resembling a big cat with a multicolored hide, found in Ancient Greek mythology.

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