The most common and most likely answer to this crossword clue is the 4 letter word DUDS
I've seen this crossword clue in The Guardian
D
U
D
S
Buddy explains!

The straight part
We know that "clothes" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case clothes = duds.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DUDS mean?
DUDS noun- A device or machine that is useless because it does not work properly or has failed to work, such as a bomb, or explosive projectile.
- A failure of any kind.
- Clothes, now always used in plural form duds.
- Clothing, especially for work or of rough appearance.